Question

What is the phenotype associated with trisomies 21, 18, and 13, respectively?

a) Klinefelter syndrome, Turner syndrome, Triple X syndrome
b) Down syndrome, Edwards syndrome, Patau syndrome
c) Huntington's disease, Marfan syndrome, Cystic fibrosis
d) Fragile X syndrome, Cri-du-chat syndrome, Prader-Willi syndrome

Answer 1

The phenotypes for trisomies 21, 18, and 13 are Down syndrome, Edwards syndrome, and Patau syndrome, respectively, which are characterized by a range of physical and intellectual impairments.

Step-by-step explanation:

The phenotype associated with trisomies 21, 18, and 13, respectively, are:

• Down syndrome, which is caused by an extra copy of chromosome 21. Individuals with Down syndrome may exhibit mental and physical impairments and have a specific facial appearance.
• Edwards syndrome, also known as trisomy 18, characterized by severe developmental delays, organ anomalies, and a high rate of mortality in infancy or early childhood.
• Patau syndrome, or trisomy 13, which involves multiple organ systems and results in severe intellectual disability and physical abnormalities in many parts of the body. Like Edwards syndrome, Patau syndrome is also associated with low survival rates.

Therefore, the correct option is b) Down syndrome, Edwards syndrome, Patau syndrome.