Final answer:
Age and genetics impact the onset of osteoporosis and osteoarthritis. In osteoporosis, the decrease in estrogen production due to menopause increases the risk, while genetics also play a role. In osteoarthritis, age-related collagen reduction in hyaline cartilage leads to cartilage damage and joint inflammation.
Step-by-step explanation:
Osteoporosis is impacted by age and genetics, specifically in relation to the production of estrogen in females. Around the age of 50, females go through menopause, which leads to a decrease in estrogen production. Estrogen promotes osteoblastic activity and production of bone matrix. Therefore, the reduction in estrogen levels increases the risk of osteoporosis. Genetics also play a role, as individuals with a family history of osteoporosis are at a greater risk of developing the disease.
Osteoarthritis, on the other hand, is influenced by age and the production of collagen in hyaline cartilage. As people age, collagen decreases in some connective tissues, including cartilage. Collagen is essential for maintaining the structure and integrity of cartilage. The reduction in collagen production can lead to cartilage damage and inflammation in the joints, contributing to the development of osteoarthritis.