Question

Select a disease clearly related to organelle failure or absence. Provide a 2-3 paragraph summary illustrating the disease, the affected organelle, reasons for organelle impact, symptoms, and treatment.

Answer 1

Mitochondrial diseases are genetic disorders that result from dysfunctional mitochondria, with Leigh syndrome being one example. Leigh syndrome affects the brain cells' mitochondria, causing symptoms such as developmental delay and muscle weakness. Treatment for this syndrome is mainly supportive.

Step-by-step explanation:

Mitochondrial diseases are a group of genetic disorders that are caused by dysfunctional mitochondria, which are responsible for producing energy in cells. One example of a disease related to organelle failure is Leigh syndrome, a rare neurological disorder that primarily affects infants and children.

Leigh syndrome is caused by mutations in mitochondrial DNA or nuclear DNA, affecting the function of mitochondria. The affected organelle in this disease is the mitochondrion, specifically the mitochondria in the brain cells.

Common symptoms of Leigh syndrome include developmental delay, muscle weakness, difficulty swallowing, and respiratory problems. Treatment for Leigh syndrome is mainly supportive, focusing on alleviating symptoms and improving the quality of life of the affected individuals.