Final answer:
A variable in computer science can hold different values at different times and can be overwritten.
Step-by-step explanation:
The statement that after a variable is defined, it holds one value which cannot be re-written is False in computer science.
In computer science, a variable is a named storage location that can hold different values at different times. Once assigned, the value of a variable can be changed or overwritten, which is a fundamental feature of variables in programming languages.
For example, in Python, you can define a variable and assign it a value like this:
my_variable = 10
Later, you can reassign a different value to the same variable:
my_variable = 20
In this case, the earlier value of 10 is overwritten by the new value of 20.