Final answer:
DNA Sequencing is the best analytical technique for detecting the mutated gene in the F1s of a sickle cell population.
Step-by-step explanation:
The best analytical technique to be used in detecting the mutated gene in the F1s of a sickle cell population is DNA Sequencing. DNA sequencing allows for the precise determination of the DNA sequence, which is essential in identifying the specific mutation causing sickle cell anemia. It enables researchers to directly read the genetic code and identify any variations or mutations.
PCR, Gel Electrophoresis, and Southern Blotting are also useful techniques in studying genetic disorders, but they have different applications. PCR is used to amplify specific DNA segments, making it useful for diagnosing sickle cell anemia. Gel Electrophoresis is used to separate DNA fragments, while Southern Blotting is used to detect specific DNA sequences.