Final answer:
Transplantation of organ or tissue between genetically different individuals of the same species is known as an allograft, and its success can be impacted by genetic differences leading to rejection by the immune system.
Step-by-step explanation:
When an organ or tissue is transplanted between genetically different individuals from the same species, it is called an allograft. This process is different from isografts, where tissue is transplanted between genetically identical individuals, such as identical twins; autografts, where tissue is transplanted from one area of an individual to another area on the same individual; and xenografts, where tissues from an animal are transplanted into a human.
The success of a transplantation, particularly allografts, is affected by genetic differences, especially in the MHC (HLA) genes, which often leads to the immune system rejecting the transplanted tissue due to recognition of the tissue as foreign. Patients usually require immunosuppressive therapy to reduce the risk of rejection.
Allografts involve tissues that are transplanted from one genetically distinct individual to another within the same species. This type of transplant has the potential for rejection due to the differences in major histocompatibility complex markers (HLAs) between the donor and recipient. Rejection occurs when the recipient's immune system recognizes the donor tissue as foreign, triggering an immune response.