Final answer:
The death of Victor's mother deeply affects him, driving his preoccupation with defeating death and influencing his quest to create life, which culminates in the birth of Frankenstein's monster.
Step-by-step explanation:
The death of Victor's mother profoundly affects him by reinforcing his obsession with overcoming death and advancing his pursuit of creating life, which later leads to the creation of the monster in Mary Shelley's Frankenstein. The event emphasizes the impact of loss and how it can deeply influence a person's choices and psychological state. It propels Victor into a quest that has far-reaching consequences, demonstrating how personal tragedy can become the catalyst for one's life work, especially in the context of literature where characters often undergo transformational journeys instigated by pivotal events.