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Two major classes of adrenergic receptors, ________ and ________ are found in the ANS?

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Final answer:

The ANS features two main classes of adrenergic receptors: alpha (α) and beta (β), which are integral in mediating sympathetic nervous system responses like the fight-or-flight reaction.

Step-by-step explanation:

In the autonomic nervous system (ANS), there are two main classes of adrenergic receptors: the alpha (α)-adrenergic and the beta (β)-adrenergic receptors. These receptors, all being G protein-coupled receptors, help mediate the effects of the sympathetic nervous system. There are three subtypes of alpha receptors, identified as α₁, α₂, and α₃ receptors, and two subtypes of beta receptors, termed β₁ and β₂.

The adrenergic system also involves a secondary signaling molecule, epinephrine, which is chemically different from norepinephrine by the addition of a methyl group (CH₃). This distinction is denoted by the prefix 'nor-' referring to norepinephrine's lack of this methyl group compared to epinephrine.

Understanding these receptors is crucial because they regulate many physiological processes. For instance, when an agonist binds to these receptors, it generally provokes a sympathetic response, such as an increased heart rate and dilation of the pupils, as part of the fight-or-flight response.

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