Final answer:
Sympathetic responses are widespread due to single preganglionic axons making multiple synapses with ganglionic neurons, amplifying the initial nervous system signal.
Step-by-step explanation:
The sympathetic responses are generally widespread because single preganglionic axons make multiple synapses with ganglionic neurons. This allows a single signal from the central nervous system to be amplified as it reaches the sympathetic ganglia, where these preganglionic axons release acetylcholine (ACh) that activates numerous postganglionic neurons. These postganglionic neurons, in turn, release norepinephrine onto target organs, creating a broad, divergent response that affects many physiological processes at once. Additionally, the adrenal gland can release norepinephrine and epinephrine into the bloodstream, further enhancing the widespread effect of sympathetic activation.