Final answer:
Dustin Locke argues that assuming that p is rationally permissible a) when it is practically certain, which means that the points and extent of our wrongness in assumptions would not make a difference in the outcome of our decision process.
Step-by-step explanation:
Dustin Locke argues that assuming that p is rationally permissible rather than engaging in probabilistic reasoning regarding p when it is practically certain. Moral or practical certainty, as understood by Locke, is epistemic in nature, even though it falls short of epistemic certainty.
According to Locke, something is practically certain if the actual epistemic probability that p differs from epistemic certainty that p only in ways that are irrelevant to the decision one currently faces.
In other words, we are practically certain if the points and extent of our wrongness in assumptions would not make a difference in the outcome of our decision process. This notion of practical certainty acknowledges that, in our decisions, we may be wrong in our assumptions, and it is impractical to demand an absolute certainty that cannot be achieved.