Final answer:
The correct answer to the question is 1) Hamlet, as the quote from Shakespeare's 'Hamlet' references the throne of Denmark's relationship with Hamlet's late father, King Hamlet.
Step-by-step explanation:
The quote "The head is not more native to the heart, The hand more instrumental to the mouth, Than is the throne of Denmark to thy father" refers to Claudius. In the context of Shakespeare's play Hamlet, this line is discussing the naturalness and legitimacy of the relationship between the throne of Denmark and Hamlet's father, who is the late King Hamlet.
Therefore, when the passage refers to "thy father," it is referring to Hamlet's father, making the correct answer choice 1) Hamlet. Claudius, who has taken the throne, is Hamlet’s uncle.