Final answer:
Some cancer cell lines do not increase glucose uptake compared to their wild type analogues. This is due to the lack of gap junctions, fewer cadherins and integrins in their membranes, which results in uncontrolled growth and metastasis.
Step-by-step explanation:
In comparison with their wild type analogues, some cancer cell lines do not increase glucose uptake. Cancer cells lack gap junctions and have fewer cadherins and integrins in their membranes, which prevents them from forming firm adherens junctions and inhibits their ability to attach firmly to the extracellular matrix. These deficiencies contribute to the uncontrolled growth and ability of cancer cells to spread (metastasize) from their original site.