Question

Are there human genes that make a cell die when they undergo copy-number alterations?

Answer 1

Yes, the p53 gene is an example of a human gene that can cause a cell to die when it undergoes copy-number alterations.

Step-by-step explanation:

Yes, there are human genes that can cause a cell to die when they undergo copy-number alterations. One example is the p53 gene, which plays a critical role in preventing cancer development. A mutated p53 gene can result in the cell behaving as if there are no mutations, allowing it to divide and propagate the mutation in daughter cells. However, a functional p53 gene will deem the cell unsalvageable and trigger programmed cell death (apoptosis) when it detects genomic errors that cannot be repaired.