Final answer:
Transcription factors can interact with co-activators to regulate gene expression. The specific associations between transcription factors and co-activators can vary depending on the context and the target genes. Research articles and databases like the TFe can provide information about these interactions.
Step-by-step explanation:
Transcription factors are proteins that bind to specific DNA sequences and regulate gene expression. They can activate or repress the transcription of genes by interacting with co-activators or co-repressors. There are many examples of transcription factors associated with co-activators, such as the interaction between the estrogen receptor and the co-activator protein SRC-1 in breast cancer. The identification of these associations is often determined through experiments and research studies on specific transcription factors and their target genes.
One resource that contains information about transcription factor-co-activator associations is the scientific literature. Research articles and review papers on transcription factors and gene regulation often discuss the interactions between transcription factors and co-activators. Additionally, databases like the Transcription Factor Encyclopedia (TFe) provide information about the interactions of transcription factors with their co-factors and binding partners. These resources can provide valuable information about which co-activators are often associated with specific transcription factors.