Question

In an enzyme that undergoes substrate inhibition, how would the presence of a competitive inhibitor affect said substrate inhibition? Would the substrate concentration at which substrate inhibition begins be affected? Would the rate of enzyme activity decrease with increasing substrate be affected?

Answer 1

In competitive inhibition, the presence of a competitive inhibitor would reduce substrate inhibition and increase the substrate concentration at which inhibition begins.

The rate of enzyme activity would decrease with increasing substrate concentration.

Step-by-step explanation:

In competitive inhibition, a competitive inhibitor binds reversibly to an enzyme's active site, blocking the substrate from binding and inhibiting the catalytic reaction.

However, increasing the concentration of the substrate can outcompete the inhibitor and restore enzyme activity.

Therefore, the presence of a competitive inhibitor would affect substrate inhibition by reducing the extent of inhibition and increasing the substrate concentration at which substrate inhibition begins.

Additionally, the rate of enzyme activity would decrease with increasing substrate concentration due to the presence of the competitive inhibitor.