Question

What about bis-tris-propane gives this compound two pKa values where other compounds have only one? How am I to choose which pKa value to use in a specific scenario?

Answer 1

Bis-tris-propane has two pKa values due to the presence of two acidic protons with different levels of acidity. The choice of which pKa value to use depends on the specific reaction or context. Strong bases would typically deprotonate the more acidic proton.

Step-by-step explanation:

Bis-tris-propane is a compound that has two pKa values because it possesses two acidic protons that can be deprotonated. These protons have different levels of acidity due to the presence of different neighboring groups and electronic effects.

The choice of which pKa value to use in a specific scenario depends on the specific reaction or context being considered. For example, if the reaction involves a strong base, the pKa value corresponding to the more acidic proton should be used.