Final answer:
Membrane-bound signaling molecules are more difficult to study compared to soluble ones due to their location and mode of action.
Step-by-step explanation:
Membrane-bound signaling molecules are more difficult to study compared to soluble ones due to their location and mode of action.
Membrane-bound signaling molecules are located on the cell membrane and require specific receptors to bind to in order to initiate a signaling pathway. These receptors are often highly specific to particular ligands, making it challenging to study their interactions.
Furthermore, membrane-bound signaling molecules often undergo complex processes such as conformational changes or interactions with G-proteins, which can be difficult to observe and study.