Final answer:
The shape of a protein is essential to its function, as alterations in shape can impact binding and functionality. Changes in protein shape may or may not affect its function.
Step-by-step explanation:
The relationship between protein shape and function is that the shape of a protein is essential to its function. A protein's shape is determined by its primary structure, which is the sequence of amino acids. Changes in protein shape can affect its function, as alterations in the active site or overall structure may prevent binding to the substrate. Therefore, option c is the correct answer: changes in protein shape may or may not affect its function.