Final answer:
The loop-1 of an integral protein is referred to as extracellular and transmembrane.
Step-by-step explanation:
The loop-1 of an integral protein can accurately be referred to as extracellular and transmembrane.
Integral proteins span the entire plasma membrane and are found in all types of biological membranes. They have hydrophobic domains that anchor them in the membrane and hydrophilic domains that interact with the aqueous extracellular fluid on one side and the cytoplasm on the other side.