Final answer:
RNA is single-stranded with a ribose sugar backbone and contains uracil in place of thymine. DNA is double-stranded with a deoxyribose sugar backbone, and its structure safeguards genetic information. The structural differences between DNA and RNA underpin their distinct roles in protein synthesis and genetic information storage.
Step-by-step explanation:
Differences Between DNA and RNA
The principal difference between DNA and RNA is that RNA is single-stranded while DNA is double-stranded. Additionally, the sugar present in the backbone of RNA is ribose, which has an extra hydroxyl group compared to the deoxyribose in DNA. This structural variation of an extra oxygen atom on the ribose sugar makes RNA less stable chemically, lending itself to temporary functions such as protein synthesis, for which RNA plays a critical role.
RNA nucleotides contain three of the same nitrogenous bases as DNA (adenine, cytosine, and guanine), while the fourth base is uracil (U) in place of thymine (T). The presence of uracil instead of thymine in RNA and the double-stranded nature of DNA contribute to the different functions and stability of these molecules. In RNA, uracil pairs with adenine during the process of protein synthesis.
RNA's structure allows it to fold upon itself, forming intricate three-dimensional shapes necessary for its function. In contrast, DNA's double-stranded helical structure serves to protect genetic information. A key role of RNA in cells is to interpret the genetic code from DNA and direct the synthesis of proteins, which determine the phenotype of organisms.