Final answer:
The induced-fit model of enzyme-substrate binding is comparable to a 'hug between two people', where both the enzyme and substrate undergo modifications to ensure a perfect fit.
Step-by-step explanation:
The induced-fit model of enzyme-substrate binding describes how an enzyme's active site can adjust its shape to better fit a substrate, much like a hand entering a glove and cause the glove to change shape for an ideal fit. Unlike the lock-and-key model, which suggests that the active site and substrate fit together without any alteration in shape, the induced-fit model allows for slight modifications in enzyme structure. This dynamic interaction enhances the enzyme's ability to catalyze its reaction. The best analogy from the given options that describes this process is like a 'hug between two people', where each can adjust their embrace to fit the other more comfortably.