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In developed countries, what percentage of diseases is caused by single gene defects?

a) 10%
b) 25%
c) 50%
d) 75%

User Polentino
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Final Answer:

In developed countries, c) 50% of diseases is caused by single gene defects.

Step-by-step explanation:

Genetic disorders caused by single gene defects are often referred to as Mendelian disorders. In developed countries, approximately 50% of diseases are not caused by single gene defects. Instead, they are influenced by a combination of genetic, environmental, and lifestyle factors. The 50% figure represents the portion of diseases with a more complex etiology, involving multiple genes and environmental interactions.

Genetic disorders with a simple Mendelian inheritance pattern, caused by a single gene defect, are relatively rare. Conditions like cystic fibrosis and sickle cell anemia fall into this category. However, they collectively constitute only a fraction of the overall disease burden. The majority of health conditions in developed countries result from a complex interplay of genetic susceptibility and environmental factors, such as diet, lifestyle, and exposure to pollutants.

Understanding the multifactorial nature of disease helps guide public health initiatives and medical research. While advancements in genetics have uncovered the genetic basis of many disorders, it's crucial to recognize the broader context in which diseases manifest. This holistic perspective informs preventive measures, personalized medicine strategies, and the development of targeted therapies for a wide array of health conditions.

In summary, the prevalence of single gene defects contributing to diseases in developed countries is approximately 50%, highlighting the importance of considering both genetic and environmental factors in healthcare approaches.

User Annika
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