Question

Is chlorpromazine bound to receptors through covalent or non-covalent bonds (such as ionic bonds, hydrogen bonds, hydrophobic interactions, van der Waals forces, etc.)?

Answer 1

Chlorpromazine binds to receptors through non-covalent bonds such as ionic bonds, hydrogen bonds, hydrophobic interactions, and van der Waals forces, rather than through covalent bonds.

Step-by-step explanation:

Chlorpromazine, a prototype of the phenothiazines class, is known to bind to receptors in a non-covalent manner, utilizing ionic bonds, hydrogen bonds, hydrophobic interactions, and van der Waals forces rather than forming covalent bonds. This allows the drug to reversibly interact with receptor sites and elicit its therapeutic effects without permanent attachment to the receptors.

Chlorpromazine's action can be characterized as neuroleptic, which has a profound impact on psychiatric conditions by inducing a state of calm without causing loss of consciousness.