Final answer:
Liver cells are most likely to have the greatest concentration of smooth endoplasmic reticulum due to their role in detoxification and synthesis of various biochemical substances.
Step-by-step explanation:
The smooth endoplasmic reticulum (SER) is involved in various cellular processes including the synthesis of carbohydrates, lipids, steroid hormones, detoxification of substances, and storage of calcium ions. Given the roles of SER, liver cells are likely to have a high concentration of SER due to their involvement in detoxification and synthesis of various substances that SER specializes in handling. Similarly, cells such as Leydig cells, which produce steroid hormones, also contain abundant SER. However, among the choices given, liver cells (answer a) are most associated with these functions and therefore tend to have the greatest concentration of SER.