Final answer:
The induced-fit model of enzyme-substrate binding can be best described by the analogy of puzzle pieces coming together.
Therefore, option C is correct.
Step-by-step explanation:
The induced-fit model of enzyme-substrate binding can be best described by the analogy of puzzle pieces coming together. In this model, the active site of the enzyme is somewhat flexible and can change shape to accommodate the substrate, similar to how puzzle pieces can fit together by adjusting their shape. This allows for a more dynamic interaction between enzyme and substrate, enhancing the enzyme's catalytic activity.