Final answer:
Epistasis is the correct explanation for the 12:3:1 phenotypic ratio of white, yellow, and green fruits in a cross of WwYy summer squash, as a dominant W allele masks the expression of the Y gene.
Step-by-step explanation:
The best explanation for the phenotypic ratio of 12 white : 3 yellow : 1 green fruits in a cross of white WwYy heterozygotes in summer squash is epistasis. This phenomenon occurs when the expression of one gene is masked by a dominant allele of another gene. In this case, the presence of a dominant W allele overrides the expression of the Y gene, resulting in white fruit.
When a cross of WwYy x WwYy is performed, we see that the W gene is epistatic to the Y gene, leading to a majority of white offspring. The yellow and green squash appear only when the W gene is homozygous recessive (ww), with the ratio of yellow (wwY_) to green (wwyy) offspring reflecting a typical monohybrid 3:1 ratio for the Y gene when its expression is not masked by the W gene.