Final answer:
An increase in blood glucose levels (Option A) is the stimulus that triggers the release of insulin from the pancreas, facilitating glucose uptake by cells and storage as glycogen, and maintaining blood glucose homeostasis.
Step-by-step explanation:
A rise in blood glucose levels triggers the release of insulin from the pancreas. The type of stimulus that initiates insulin release is an increase in blood glucose levels.
Insulin facilitates the uptake of glucose by cells and its storage as glycogen in the liver, thus lowering blood glucose levels. This regulatory mechanism is crucial for maintaining homeostasis in the body.
When blood glucose levels become too low, the hormone glucagon is released by the pancreas to raise blood glucose levels through the processes of glycogenolysis and gluconeogenesis.
Hence, the correct answer is Option A.