Question

Changes in the body can be mediated by direct or indirect mechanisms. What facilitate(s) direct mediation of change by hormones?

a) Second messengers
b) Intracellular receptors
c) Enzyme activation
d) Membrane receptors

Answer 1

Intracellular receptors facilitate the direct mediation of change by hormones, which results in altered gene expression inside the target cell.

Step-by-step explanation:

Direct mediation of change by hormones in the body is facilitated by intracellular receptors. These receptors are located either in the cytoplasm or in the nucleus of the target cells. When lipid-soluble hormones enter a cell, they bind to these intracellular receptors, causing a change in gene expression which directly affects the cell's functions.

This differs from cell surface receptors, which facilitate indirect mediation through cell-signaling pathways involving second messengers like cAMP, following the hormone binding.Direct mediation of changes by hormones is facilitated by membrane receptors. These receptors are located on the cell surface and bind to hormones, triggering signaling pathways that result in cellular changes. This direct mechanism allows hormones to quickly and directly impact target cells.