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Describe how hormone receptors can play a role in affecting the size of the responses of tissues to hormones.

a) Receptors can increase tissue sensitivity by amplifying the signal
b) Receptors have no impact on tissue responses to hormones
c) Receptors block hormone signals to tissues
d) Receptors are only present in the endocrine glands

1 Answer

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Final answer:

Hormone receptors control cellular responses to hormones by altering the number of receptors through up-regulation or down-regulation, affecting tissue sensitivity. This modulation of receptor numbers allows cells to appropriately respond to varying hormone levels, ensuring physiological balance.

Step-by-step explanation:

Hormone receptors play a crucial role in regulating the response of target tissues to hormones. By binding to specific receptors, hormones can only influence cells equipped with these receptors, thus ensuring that the hormonal signal is delivered specifically and efficiently. Hormone receptors can amplify the signal (up-regulation) or de-amplify it (down-regulation), altering tissue sensitivity and the magnitude of the cellular response.

For instance, an increase in hormone levels may lead to an increase in the number of receptors on the target cells, known as up-regulation, making the cells more sensitive to the hormone. Conversely, if there are excessive hormone levels, cells may reduce the number of receptors in a process known as down-regulation, which makes the cells less sensitive. These mechanisms ensure that cells can effectively manage their response to fluctuations in hormone levels.

Additionally, the location of the hormone receptor (on the cell surface or inside the cell) and the specific signaling pathways activated upon hormone binding can determine how the cell will respond, either by changing its functionality directly or by altering gene transcription. This fine-tuning of cellular activity is essential for maintaining homeostasis and proper physiological function.

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