Final answer:
Treponemal and non-treponemal serological testing can be used to test for Syphilis.
Step-by-step explanation:
Treponemal and non-treponemal serological testing can be used to test for Syphilis.
For the diagnosis of syphilis, two types of serological tests - treponemal and nontreponemal - are commonly used. Nontreponemal tests, such as the Venereal Disease Research Laboratory (VDRL) and rapid plasma reagin (RPR) tests, detect nonspecific antibodies produced during the infection. On the other hand, treponemal tests, including particle agglutination, immunofluorescence, enzyme reactions, and chemiluminescence immunoassays, measure antibodies directed against the specific antigens of T. pallidum.
Both treponemal and nontreponemal tests should be used for diagnosis as they have different limitations that can result in false positives or false negatives.