Question

Which of the following is a genetic disease that results in lack of production of antibodies?

a) DiGeorge syndrome
b) X-linked agammaglobulinemia
c) Hyper-IgM syndrome
d) Severe combined immunodeficiency (SCID)

Answer 1

X-linked agammaglobulinemia is a genetic disease causing the lack of antibody production due to defective B cell differentiation.

Step-by-step explanation:

The genetic disease that results in the lack of production of antibodies is X-linked agammaglobulinemia. This condition is characterized by the absence of immunoglobulin in the serum and is caused by a defective differentiation of B cells. X-linked agammaglobulinemia, discovered by Ogden C. Bruton in 1952, often leads to severe infections early in life and is potentially deadly due to the inability to produce specific antibodies.