Final answer:
Benzimidazoles are the antihelminthic drugs that inhibit neuronal transmission in helminths by targeting ß-tubulin, affecting the formation of microtubules and glucose uptake, leading to parasite death.
Step-by-step explanation:
The drug class specifically known to inhibit neuronal transmission in helminths is benzimidazoles. These antihelminthic drugs, including mebendazole and albendazole, function by targeting the ß-tubulin within the helminths. This action prevents the proper formation of microtubules, particularly in the intestinal cells of the worms, which subsequently affects glucose uptake, leading to their death. Benzimidazoles also impact a range of other organisms, including protozoans, but their selective action is particularly effective against helminths. While they are potent antiparasitic agents, the potential side effects may include liver damage and bone marrow suppression.