Final answer:
DNA polymerase is the enzyme that replaces the RNA nucleotides in a primer with DNA nucleotides.
Step-by-step explanation:
The enzyme that replaces the RNA nucleotides in a primer with DNA nucleotides is DNA polymerase. DNA polymerase is responsible for synthesizing a new DNA strand by adding complementary nucleotides to the existing template strand. In this case, it replaces the RNA nucleotides in the primer with DNA nucleotides to form a complete DNA strand.