Final answer:
John Locke did not actively challenge the status of women in the early American republic, unlike Susan B. Anthony, Elizabeth Cady Stanton, and Abigail Adams, who were advocates for women's rights.
Step-by-step explanation:
The individual from the options provided who did not actively challenge the status of women in the early American republic is John Locke. Notably, Susan B. Anthony and Elizabeth Cady Stanton were both staunch advocates for women's rights, playing significant roles in the suffrage movement. Abigail Adams, in her personal correspondence, did call for remembering the ladies in the new code of laws during the revolutionary period. However, John Locke, a 17th-century philosopher, although influential in many aspects of the foundation of American political theory, did not play an active role in challenging the status of women during the time of the early American republic.