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Autoantibodies are probably involved in ________.

a) Allergic reactions
b) Autoimmune diseases
c) Viral infections
d) Antibiotic resistance

1 Answer

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Final answer:

Autoantibodies are involved in autoimmune diseases, where the immune system erroneously targets the body's own tissues, as seen in conditions like myasthenia gravis and systemic lupus erythematosus.

Step-by-step explanation:

Autoantibodies are probably involved in autoimmune diseases. These are antibodies that the immune system mistakenly directs against the body's own tissues. For example, in myasthenia gravis, an autoimmune disease, muscle cell receptors that induce contraction in response to acetylcholine are targeted by antibodies, leading to muscle weakness. Another example is systemic lupus erythematosus, where a diffuse autoantibody response to the individual's own DNA and proteins results in various systemic diseases. Rheumatic fever, which can damage the heart, especially the heart valves, is another autoimmune condition triggered by antibodies that cross-react with an antigenic component of heart myosin after a Streptococcus bacterial infection.

Therefore, when considering the choices provided:

  • Allergic reactions - Incorrect, as allergies are hypersensitivity reactions to external antigens, not self-antigens.
  • Autoimmune diseases - Correct, as autoantibodies are against self-antigens.
  • Viral infections - Incorrect, as these generally involve immune responses against viral antigens.
  • Antibiotic resistance - Incorrect, as this involves bacteria's ability to survive despite the presence of antibiotics, not the presence of autoantibodies.

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