Final answer:
In the ABCDE Cancer Checklist, the letter 'C' stands for Color, which is used to detect early signs of melanoma in moles.
Step-by-step explanation:
In the ABCDE Cancer Checklist established by the American Cancer Society, which is intended to help with the diagnosis of early-stage melanoma, the letter 'C' stands for Color. This checklist is a mnemonic aid for remembering the warning signs of melanoma, with each letter corresponding to a particular characteristic to watch out for in moles on the skin. 'C' refers to the color, indicating that if the color of a mole is varied or includes different shades of brown or black, it could potentially be a warning sign of melanoma.