Question

Different MHC class I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.

a) Mismatched MHC triggers an immune response against the transplant
b) MHC molecules are not involved in immune reactions
c) Transplants have no influence on MHC expression
d) Mismatched MHC enhances organ acceptance

Answer 1

Mismatched MHC triggers an immune response against the transplant.a) Mismatched MHC triggers an immune response against the transplant

Step-by-step explanation:

The reason different MHC class I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue is because mismatched MHC triggers an immune response against the transplant. MHC molecules are responsible for presenting antigens to the immune system, and when the MHC molecules on the donated organ or tissue are recognized as non-self by the recipient's immune system, it triggers an immune response to reject the transplant.