Question

When is fibrin produced during the coagulation cascade?

-extrinsic pathway
-intrinsic pathway
-common pathway
-both intrinsic and extrinsic pathways

Answer 1

Fibrin is produced during the intrinsic pathway, extrinsic pathway, and common pathway of the coagulation cascade.

Step-by-step explanation:

In the coagulation cascade, fibrin is produced during the both intrinsic and extrinsic pathways, as well as the common pathway. Once factor X has been activated by either the intrinsic or extrinsic pathway, the enzyme prothrombinase converts factor II, the inactive enzyme prothrombin, into the active enzyme thrombin. Thrombin then converts factor I, the soluble fibrinogen, into insoluble fibrin protein strands. Factor XIII stabilizes the fibrin clot.