Final answer:
The Zona Fasciculata, located in the adrenal cortex, primarily synthesizes glucocorticoids such as cortisol and corticosterone, which are involved in glucose metabolism and the body's response to stress.
Step-by-step explanation:
Hormones Synthesized in the Zona Fasciculata:
The Zona Fasciculata is the intermediate region of the adrenal cortex known for producing hormones called glucocorticoids, which are critical in regulating glucose metabolism. The most well-known glucocorticoid produced by the zona fasciculata is cortisol, an essential hormone released in response to stress. This hormone helps control the metabolism of proteins, fats, and sugars in the body, elevates blood glucose levels, and has anti-inflammatory effects on the immune system. Another glucocorticoid produced here, although in smaller amounts, is corticosterone.
Regulation of glucocorticoid production is orchestrated by the hypothalamus and the anterior pituitary gland through secretion of CRH (Corticotropin-Releasing Hormone) and ACTH (Adrenocorticotropic Hormone) respectively, especially in response to long-term stressors.