Final answer:
The nurse should stop the IV infusion immediately as the patient's symptoms suggest a serious allergic reaction. After stopping the infusion, the patient should be assessed and appropriate treatment should be provided based on their condition.
Step-by-step explanation:
If a patient reports feeling hot, itchy, and has difficulty breathing after starting an IV antibiotic infusion, the nurse should stop the infusion immediately. These symptoms could indicate a hypersensitivity reaction or anaphylaxis, which is a serious and potentially life-threatening allergic reaction. The nurse should assess the patient's airway, breathing, and circulation, provide supportive care immediately, and notify the physician. Treatment may include the administration of antihistamines, corticosteroids, and epinephrine, depending on the severity of the reaction and the patient's clinical condition.