Final answer:
True, Friedrich Wöhler demonstrated the synthesis of urea, an organic compound, from inorganic materials in 1828, refuting vitalism.
Step-by-step explanation:
The statement that Friedrich Wöhler refuted the scientific concept of vitalism during the early 1800s by proving that organic molecules could be synthesized outside a living organism is True. Wöhler's experiment in 1828 involved the synthesis of urea, an organic compound, from inorganic starting materials - specifically silver cyanate (AgOCN) and ammonium chloride (NH4Cl). This groundbreaking work demonstrated that organic molecules do not require a 'vital force' from living organisms for their creation, thereby countering the theory of vitalism and advancing the understanding of organic chemistry.