Question

How to avoid CMV transmission with PRBCs?

a) Washing the PRBCs before transfusion
b) Leukoreduction
c) Irradiation of blood products
d) Using a CMV-negative donor

Answer 1

To avoid CMV transmission with PRBCs, you can wash the PRBCs before transfusion, perform leukoreduction, irradiate the blood products, or use a CMV-negative donor.

Step-by-step explanation:

To avoid CMV transmission with PRBCs, there are several measures that can be taken:

1. Washing the PRBCs before transfusion: This can help remove any CMV present on the surface of the blood cells.
2. Leukoreduction: This process involves removing white blood cells from the PRBCs, as CMV is often carried by these cells.
3. Irradiation of blood products: By exposing the PRBCs to radiation, any CMV present in the blood can be destroyed.
4. Using a CMV-negative donor: Choosing a donor who has tested negative for CMV can significantly reduce the risk of CMV transmission.