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What factors influence Minimum Alveolar Concentration (MAC)?

Factors that increase MAC
Factors that decrease MAC
Factors that do not affect MAC
Factors that solely affect MAC during surgery with nitrous oxide administration

User Rohlik
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Final answer:

Minimum Alveolar Concentration (MAC) can be influenced by a variety of factors, including body temperature, drug and hormone levels, and concurrent use of other anesthetic agents. Age can either increase MAC in adults or decrease it in elderly patients, whereas height, weight, or fat distribution typically do not affect MAC. Nitrous oxide use during surgery decreases the MAC for other volatile anesthetics.

Step-by-step explanation:

The Minimum Alveolar Concentration (MAC) is an important concept in anesthesiology, representing the concentration of an inhalational anesthetic needed for a specific effect. There are several factors that can influence MAC.

  • Factors that increase MAC: Increased ambient temperature, increased levels of certain hormones such as epinephrine, and increased age in adults all can lead to higher MAC values.
  • Factors that decrease MAC: Decreases in body temperature, use of additional sedative drugs or opioids, acute alcohol intoxication, and advanced age in persons over 65 can lower MAC requirements.
  • Factors that do not affect MAC: An individual's height, weight, or fat distribution generally does not have a direct impact on MAC.
  • Factors with nitrous oxide: During surgery with nitrous oxide administration, concurrent use of other volatile anesthetic agents will decrease the MAC for these agents.

Understanding these factors is essential for patient safety and the fine-tuning of anesthesia during procedures.

User Tokunbo
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