Final answer:
The correct action when a sharps container is 3/4 full is to seal it and replace it with a new one, to avoid needle-stick injuries and ensure safe disposal.
Step-by-step explanation:
When a sharps container is 3/4 full, the appropriate action to take would be option A) Seal and replace. This is because overfilled sharps containers can pose a significant needle-stick injury risk to those handling them. It's important to follow proper disposal procedures for biomedical waste, ensuring that it is managed safely to protect healthcare workers, sanitation staff, and the environment from potential harm. Ignoring the level, shaking to make space, or disposing of sharps in regular trash are all unsafe practices that could lead to injuries or contamination.