Question

Which statement is true of antibody IgE?

A) IgE is mainly found in secretions such as tears and saliva.
B) IgE is passed from mother to fetus during pregnancy.
C) IgE is the most abundant antibody in blood plasma.
D) IgE can fix complement.
E) IgE is involved in allergies.

Answer 1

The true statement about IgE is that it is involved in allergies, as it mediates allergic responses by binding to mast cells and basophils to release inflammatory mediators.

Step-by-step explanation:

The statement that is true of antibody IgE is: E) IgE is involved in allergies. IgE is present in the serum in small quantities and plays a pivotal role as an allergy mediator. Unlike IgA, which is found in secretions like saliva and tears and provides mucosal immunity, IgE binds to mast cells and basophils, and upon interacting with an antigen, it triggers the release of inflammatory mediators that cause allergic reactions. Furthermore, IgE does not fix complement. The IgE-mediated allergic response is also referred to as immediate hypersensitivity.