Final answer:
The Amazon River system originates from Lake Titicaca in the Andes Mountains in Peru.
Step-by-step explanation:
The Amazon River system originates from Lake Titicaca located in the Andes Mountains in Peru. It is a glacial stream that starts approximately 150 miles from the Pacific Ocean. The Amazon and its many tributaries drain the entire interior region of South America, covering 40 percent of the continent.