Final answer:
The presence of granulated colonies in sputum, spinal fluid, and biopsies allows for a straightforward diagnosis of coccidioidomycosis. Serological tests for antibody production are commonly used for diagnosis, as culturing the fungus can be dangerous. Treatment for disseminated infections usually involves intravenous antifungal drugs like amphotericin B.
Step-by-step explanation:
The presence of distinctive granulated colonies in sputum, spinal fluid, and biopsies gives a straightforward diagnosis of coccidioidomycosis. In the case of coccidioidomycosis, culturing clinical samples can be a dangerous process due to the infectious nature of the fungus. Therefore, serological tests for antibody production are more commonly used for diagnosis. Mild cases of coccidioidomycosis may not require intervention, but disseminated infections can be treated with intravenous antifungal drugs like amphotericin B.