Final answer:
The FDA primarily enforces the use of gloves in clinical settings, with guidelines informed by the CDC, while end-users in healthcare facilities are responsible for adherence to these regulations.
Step-by-step explanation:
The agency responsible for enforcing the use of gloves in a clinical setting is largely the Food and Drug Administration (FDA). The FDA sets forth regulations and standards for the safe use of medical devices and equipment, which includes personal protective equipment like gloves. Additionally, protocols for maintaining a hygienic clinical environment, including the use of gloves, can be informed by guidelines set by the Centers for Disease Control and Prevention (CDC). It is important to note that while agencies provide regulations and guidelines, the end-users such as hospitals and their staff have the ultimate responsibility to adhere to these standards to ensure patient safety. Failure to comply can result in liability for the healthcare providers if patients are harmed as a result of noncompliance.