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Which diuretics cause Hypochloremic metabolic alkalosis?

User Tyeasha
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Final answer:

Hypochloremic metabolic alkalosis can be caused by loop diuretics like Furosemide and thiazide diuretics such as Hydrochlorothiazide, which inhibit the reabsorption of sodium and chloride ions in the kidneys, leading to increased urination and altered blood electrolyte levels.

Step-by-step explanation:

The student's question concerns which diuretics cause Hypochloremic metabolic alkalosis. This condition is characterized by an elevated blood pH due to excessive loss of chloride (Cl-) ions, which can be induced by certain diuretic medications. Diuretics that commonly lead to Hypochloremic metabolic alkalosis include loop diuretics and thiazide diuretics. Loop diuretics such as Furosemide (Lasix) inhibit the reabsorption of sodium (Na+) and chloride ions in the ascending limb of the loop of Henle. Thiazide diuretics like Hydrochlorothiazide (Esidrix, Hydrodiuril) also reduce sodium and chloride reabsorption but in the distal convoluted tubule. Both types of diuretics increase urine output and can deplete potassium, contributing to an alkalotic state in the body.

User William Lahti
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