Final answer:
Osteoclasts are responsible for the breakdown of bone in a process called bone resorption, which is necessary for bone remodeling. They work with osteoblasts to maintain the balance and reshaping of bone.
Step-by-step explanation:
Osteoclasts, which are multinucleated cells derived from monocytes and macrophages, are responsible for the breakdown of bone in a process called bone resorption. They play a key role in bone remodeling by dissolving old, injured, or unnecessary bone to make room for new bone formation. Osteoclasts work in conjunction with osteoblasts, which are responsible for bone formation, to maintain the balance and reshaping of bone throughout life.